Abstract

DURING the past 25 years, the incidence of<i>Salmonella</i>infections, as reported by the Communicable Disease Center in Atlanta,<sup>1</sup>has shown a 20-fold increase. During the same period of time, there has been a steady decline in the incidence of typhoid fever until fewer than 500 cases were reported in 1964. In 1951, there were only 1,500 cases of salmonellosis reported in the United States. By 1965, this had risen to 20,000 cases with an estimated one in ten cases being reported.<sup>2</sup>Accompanying this marked increase in the incidence of salmonellosis is the sharp rise in numbers of serotypes. There were 400 serotypes reported in 1960.<sup>3</sup>Today, there are over 1,200 different subspecies, all of which have either been reported to be pathogenic or found in a carrier state for man.<sup>2</sup>The problem of good public health control has become increasingly difficult since a large reservoir

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