Abstract

The clinical findings and diagnosis of insulinomas are reviewed. The use of selective celiac and superior mesenteric angiography is an important adjunct in the diagnosis, localization, and treatment of islet cell tumors. Two cases illustrating enucleation and two cases illustrating two types of resection of the pancreas are presented. A blind distal resection is recommended for patients with organic hypoglycemia when no tumor can be located at operation. It may be necessary to resect up to 95 per cent of the distal pancreas. Distal resection is performed for palpable adenomas in the body and tail of the pancreas which are impossible to enucleate. Pancreatoduodenectomy is performed for palpable lesions in the pancreatic head which are impossible to enucleate.

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