Surgery of papillary thyroid microcarcinoma

Abstract

Different countries are currently reporting asubstantial increase in the incidence rates of papillary thyroid microcarcinoma (PTMC). Presentation of diagnosis and surgical therapy of PTMC and discussion of amore conservative approach, such as active surveillance. Overview of the current guidelines from different countries and analysis of recent publications reporting the results of active surveillance of PTMC from Japan, Korea and the USA. The majority of international guidelines for PTMC recommends thyroid lobectomy as the gold standard. Active surveillance as an alternative procedure is described in the Japanese guidelines (JSTS/JAES). Present surveillance studies including more than 1700 patients report atumor growth in 8-14% of the cases during amedian follow-up of up to 75months. Tumor growth and lymph node metastases are detected most frequently in younger patients (below 40-50years). Active surveillance might serve as an alternative treatment option for older patients with PTMC. Since the median follow-up periods are currently not long enough, it seems difficult to draw definite conclusions of this procedure right now.