Abstract

<p>This editorial article reports the evidence behind the pre-surgical evaluation and epilepsy surgey in human patients with drug-resistant idiopathic epilepsy and how this could potentially benefit veterinary patients.</p><p>(Editorial article - Abstract not applicable)</p>

Highlights

  • The aim of epilepsy surgery is to completely remove the epileptogenic area while avoiding neurological deficits (Zhang et al, 2014)

  • Post-operative results have showed that seizure freedom has reached rates as high as 60% to 90% and 40% to 60 % in individuals with temporal and extra-temporal lobe epilepsy, respectively (TellezZenteno, 2005)

  • In another study (Knowlton et al, 2008a, Knowlton et al, 2008b) in which MEG was compared to intracranial electroencephalography (icEEG) in 77 epileptic patients (39 with temporal lobe epilepsy, 33 with extra-temporal lobe epilepsy and 5 with non-localized epilepsy), it was found that MEG and icEEG localized the seizure focus in 61% and 70.1% cases, respectively

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Summary

Introduction

The aim of epilepsy surgery is to completely remove the epileptogenic area while avoiding neurological deficits (Zhang et al, 2014). The IZ can be evaluated by interictal non-invasive neuroimaging techniques such as scalp electroencephalography (EEG), magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) or combination of them as well as invasive intracranial electroencephalography (icEEG); the latter has high sensitivity and specificity (Blount et al, 2008, Vulliemoz et al, 2011) and is considered as the “gold standard” for defining the epileptogenic area (Blount et al, 2008).

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