Abstract

The results of temporal resection for medically intractable epilepsy in 20 children less than age 5 years with at least 2 years follow-up are reported from Miami Children's Hospital, Florida.

Highlights

  • The results of temporal resection for medically intractable epilepsy in 20 children less than age 5 years with at least 2 years follow-up are reported from Miami Children's Hospital, Florida

  • A diffusion tensor imaging technique was compared with conventional MRI to measure and quantify corticospinal dysgenesis in 12 patients with congenital hemiplegia and 12 matched control subjects, in a study at Universite Catholique de Louvain, Brussels, Belgium

  • A symmetry index computed between the area of the contralateral and ipsilateral corticospinal tracts was similar for the two methods, but the diffusion tensor imaging indexes were significantly smaller

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Summary

Introduction

The results of temporal resection for medically intractable epilepsy in 20 children less than age 5 years with at least 2 years follow-up are reported from Miami Children's Hospital, Florida. A diffusion tensor imaging technique was compared with conventional MRI to measure and quantify corticospinal dysgenesis in 12 patients with congenital hemiplegia and 12 matched control subjects, in a study at Universite Catholique de Louvain, Brussels, Belgium. A symmetry index computed between the area of the contralateral and ipsilateral corticospinal tracts was similar for the two methods, but the diffusion tensor imaging indexes were significantly smaller. This suggests that the use of the conventional MRI measurement of the cross-sectional area of cerebral peduncles on T1 MRI might lead to an underestimate of cortical dysgenesis.

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