Abstract
Surfactant protein C(SP-C)is found to be expressed only in the alveolar type Ⅱ cells(AECⅡ), surfactant protein C gene mutations are found to be associated with Children interstitial lung disease.This review discusses the mechanism, diagnosis and therapy of the interstitial lung disease induced by the surfactant protein C gene mutations. Key words: Children; Interstitial lung disease; Surfactant protein C; Gene mutation
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