Abstract
Meconium aspiration can cause lethal respiratory failure in term infants. Recent large trials have demonstrated that the interventions to prevent meconium aspiration syndrome (MAS) — intra-amniotic saline infusions prior to delivery, airway suction on the perineum at delivery, or intubation and tracheal suction of vigorous infants — do not prevent MAS. Nevertheless, in the US, the syndrome is disappearing, presumably because there are fewer post-dates deliveries, and asphyxia during labor is detected and treated more effectively.
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