Abstract

In this paper, surfaces of thin films prepared from blends of collagen, hyaluronic acid, and chitosan and modified by neodymium laser radiation were researched. To evaluate the laser beam effect on the surface structure, scanning electron microscopy (SEM) imaging and infrared spectroscopy (FTIR-ATR) were employed. The results demonstrated that during laser treatment the specimens lost water due to the evaporation process. SEM images revealed some changes in the biopolymer films structure. After laser treatment, the micro-foam formation was observed on the biopolymeric films. The micro-foaming in films based on ternary blends was more extensive than in those made of a single biopolymer. The results of this study indicate that collagen, hyaluronic acid, and chitosan materials can be modified with laser treatment. Such treatment can be used for material modification for potential biomedical purposes.

Highlights

  • Modification of Collagen, HyaluronicSurface properties of new materials are of significant importance for several reasons [1].The surface plays a pivotal role in biomedical applications of new materials prepared with the use of biopolymers

  • The purpose of this work was to investigate the impact of laser radiation on the structure of biopolymeric films based on hyaluronic acid, collagen/hyaluronic acid, and collagen/hyaluronic acid, with the addition of chitosan

  • The treatment of biopolymeric films made of hyaluronic acid, and those made of the blend of collagen and hyaluronic acid as well as the ternary Coll/Hyaluronic acid (HA)/chitosan blend with pulse neodymium laser radiation, led to the alterations of the surface properties

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Summary

Introduction

Surface properties of new materials are of significant importance for several reasons [1]. The surface plays a pivotal role in biomedical applications of new materials prepared with the use of biopolymers. Laser treatment of biopolymer materials is one of the physico-chemical methods of surface treatment [2]. Lasers are used to design the surfaces of different types of materials and can manipulate roughness and wetting characteristics [2,3]. Applications for laser-structured surfaces are emerging in different types of areas, including biomedical field, water harvesting, spectroscopic analysis, antibacterial and antifungal, and oil/water separation, etc., which have been observed recently [2,5]. Structured surfaces of several biopolymeric materials allow the application of commonly used biopolymers in an extensive range of specialized fields

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