Abstract
Singlet oxygen plays a critical role in a great number of applications including photodynamic therapy of cancers, photodynamic inactivation of microorganisms, photooxidation, and photodegradation of polymers. Herein we demonstrate a general platform to improve singlet oxygen production via resonance coupling between surface plasmon and photosensitizers. By loading photosensitizers into mesoporous silica containing silver nanoparticles, strong resonance coupling between the photosensitizers and the silver core markedly increases the singlet oxygen production, by up to three orders of magnitude in some cases. It is observed that the more spectral overlap between the surface plasmon resonance spectrum of the silver core and the photosensitizers' absorption spectra, the greater the singlet oxygen production. The as-synthesized hybrids have shown exceptionally high photoinactivation efficiency against both Gram-positive and Gram-negative bacteria. This work establishes a general platform to improve singlet oxygen production and to develop more effective and efficient hybrid photosensitizers for broad-spectrum photodynamic inactivation of bacteria.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.