Abstract
Resistive pulse sensing is a particle analyzing technique using small pores. When particles pass through a pore, interruptions in ion current flow are recorded as passing particles. One problem that arises is that measurements can be prevented by clogging from impurity adsorption on the pore surface. This problem is strongly dependent on non-specific adsorption forces, such as hydrophobic interactions; therefore, altering the physical characteristics of the pore surface can address this problem. In this work, we demonstrate an effective method of surface modification to reduce pore clogging.
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