Surface lipids of Kalanhoe as a material for nanoparticles preparation

Abstract

The purpose of the investigation was to elaborate the methods of extraction of surface lipids from Kalanchoe Degremona plants and preparation of solid lipid nanoparticles containing a dirhenium(III) cluster compound. The procedure of growing plants and increasing the quantity of surface lipids by means of adaptation biochemistry to toxicants was used in this work. Data on the quantities of extracts, IR-spectra, and GC-MS-data of hydrocarbons and oxocompounds of surface lipids obtained were presented. An increase in the total number of surface lipids and an insignificant change in heterogeneity under the influence of monochlorobenzene exposition were shown. The absence of differences in the ratio of the intensity of the characteristic bands in the FTIR spectra allowed concluding that the toxicant did not affect the qualitative composition of the surface lipids. The nanoparticles (with a size of 14540 nm) with high encapsulation efficiency were prepared, these nanoparticles containing the dirhenium(III) cluster compound that previously showed a cytostatic action in experiments in vivo.