Surface-enhanced Raman imaging through sprayed probes for the application in chemical visualization of methamphetamine within fingerprints.

Abstract

For fingerprint-involved forensic investigations, cyanoacrylates and inorganic nanophosphors are mostly used for fingerprint visualization. However, methods to simultaneously report fingerprint images and the corresponding specific chemical information have yet to be realized. In this work, chemical visualization of the analytes in fingerprints is achieved through surface-enhanced Raman spectroscopy (SERS) measurements with the aid of spray-dispersed gold nanorods (AuNRs). The optimal coverage of AuNRs was studied by theoretical simulations and experimental operations. A rapid sampling of fingerprints with the chemical of interest was developed by tuning the spray parameters. In particular, the SERS imaging of methamphetamine in fingerprint latent was attempted by addressing the SERS spectral features of methamphetamine. This chemical visualization method reflects both the graphical and chemical characteristics of fingerprints in a single batch measurement, in which methamphetamine can be detected and mapped at the concentration of 10-5M. The data processing approach was also modified by employing relevant logical judgments. The improved SERS images with sharpened patterns of fingerprints were obtained by involving the scored multi-peak judgments.