Surface Chemical Modification of Crosslinked Polystyrene Microspheres and Immobilization of Pyridyl Porphyrins

Abstract

Crosslinked polystyrene microspheres(CPS) were first chloromethylated with non-carcinogenic 1,4-bis(chloromethoxy) butane(BCMB) to form chloromethylated microspheres(CMCPS).Then quaternization reaction between CMCPS microspheres and 4-pyridylaldehyde was carried out to modify the CPS microspheres with 4-pyridylaldehyde(PyAL-CPS).The effects of main factors on the quaternization reaction were examined,and the synthetic conditions were optimized.The suitable temperature and appropriate solvent are 60 ℃ and CCl4,respectively.Finally,Alder reaction at the interface of solid/solution between 4-pyridylaldehyde on the surface of modified microspheres and pyrrole was performed to form the functional microspheres(PyP-CPS),on which the formation of pyridyl porphyrin(PyP) could be achieved.The PyP-CPS formation were characterized by using IR and UV-Vis while and the loading of PyP was demonstrated by forming Zn-PyP complex.