Abstract
<span lang="EN-US">Of many compounds materials, </span><span lang="PT-BR">metallic biomaterial is widely used in human medical devices. An implant material's corrosion resistance impacts its flexibility and longevity. This corrosion resistance is also an important consideration for biocompatibility. This biomaterial contains stainless steel whcih may corrode after being installed in the human body since the passivity of stainless steel disappears when it is exposed to acids in the human body for a long duration. In addition, lacks of oxygen inhibits the formation of a new Cr<sub>2</sub>O<sub>3</sub> layer for corrosion protection. Based on this phenomenon, an advance treatment is required to improve the resistance corrosion of implant. This study investigates the effect of the concentration and duration of chitosan on the thickness and corrosion resistance of biomaterials. The concentration of chitosan used was 0.08</span><span lang="PT-BR">%, 0.16</span><span lang="PT-BR">%, and 0.24</span><span lang="PT-BR">% while the voltage used was constant at 10 V. The test results demonstrated the lowest corrosion rate occrured for 0.24 % chitosan concentration with 30 minutes coating duration. The lowest corrosion rate achieved was 0.014 mmpy and the maximum thickness was 75.4 μm. This study could be then used as a new solution to increase the safety of existing implants using biodegradable and non-toxic compounds. The next experiment should be implantation in real human body.</span>
Highlights
A biomaterial is a substance which inactively interacts with the biological system [1–4]
The test found that the chitosan concentration of 0.24 % resulted in the lowest corrosion rate (CR), i. e. 0.01486 mmpy (Table 2)
This study found that the greater the chitosan concentration, the higher the corrosion resistance of the specimen which is due to the thicker chitosan layer deposited on surface of the 316L stainless steel
Summary
A biomaterial is a substance which inactively interacts with the biological system [1–4]. Before the arrival of a new biomaterial into the market, numerous issues have been discussed, e.g. its anatomical position, tissue function, pathology composition, mechanical and other criteria for properties, toxicology, biocompatibility, healing mechanism, ethics, standardisation and regulatory procedures. Biocompatibility considers the processes between hydrocarbons and the biomaterial itself. A biocompatible substance performs in a certain application with an acceptable host response, i.e. a minimal interruption to normal body function. The biocompatibility of a drug is determined by two main factors, i.e. host reactions caused by this material and deterioration of the body environment. It is important to weigh all variables since biomaterials appropriate for implants are a sufficiently corrosive medium to the human body. That is reasoning intensively selection of modern and effective biomaterials [5,6]
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