Abstract

In this study, surface and biological properties of collagen/thymol materials were evaluated. Antimicrobial properties of materials were evaluated by measuring ATP level and enzymatic activity of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa after the contact with materials. Surface properties were analyzed by AFM spectroscopy and contact angle measurements. Materials were characterized by rough surface and hydrophobicity of materials increase with increasing thymol amount. Prepared materials were permeable for gaseous exchange, but sufficiently prevented from the secondary infection. Collagen/thymol caused haemolysis of blood cells, but changing the non-ionic surfactant may improve the blood biocompatibility parameter.

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