Sur le purpura hémorragique observé dans l'Azarbaidjan-Est de l'Iran

Abstract

Durant les années 1974 et 1975, 43 cas de la maladie connue sous le nom autochtone de « Hasbeh Ghara-Mikh ont été étudiés dans l'Azarbaidjan-Est de l'Iran. La maladie est un purpura thrombocytopénique qui ne peut pas être causé par un agent viral mais pourrait être dû à un spirochéte d'une espèce nouvelle. An endemic focus of hemorragic purpura is reported to exist for several years in the North-Eastern part of iranian Azerbeidjan, at an altitude of 1.700 m, among farmers living together with domestic animal in crude brick houses were ectoparasites are abundant. The disease has a seasonal periodicity, from June to August ; both sexs are equally affected, mainly young people ; sporadic cases often occur simultaneously in distant villages. The main clinical symptoms are purpura and hemorrages with thrombocytopenia and extended bleeding time. No arbovirus has been isolated and serological tests for Crimean Hemorragic Fever remained negative. From one of the patients, in the acute phase, one spirocheta has been isolated whose etiologic role is discussed. This spirocheta is different from all others previously known in Iran. Its possible vectors are yet unknown.