Sur la solubilisation micellaire des acides palmitique, stéarique et oléique dans les solutions d'acides biliaires conjugués

Abstract

Oleic acid increases the solubility of saturated fatty acids in micellar solutions of conjugated bile acids by lowering the melting point. It is the liquid part of the saturated and unsaturated fatty acid mixtures which is preferentially incorporated into the conjugated bile acid micelles. When only a limited quantity of these bile acids is present, the liquid fatty acid mixtures are partly in the form of particles coarser than the ordinary micelles, but smaller than 100 mμ. Analogous results are found with mixtures of stearic acid and monoolein-1.