Abstract

Summary of main observation and conclusionWater‐soluble 2,6‐helic[6]arene was used to construct supramolecular vesicles via host‐guest interaction. Water‐soluble 2,6‐helic[6]arene was discovered to be high affinity host for suitable biomarkers. Supramolecular vesicles were responsive to multiple stimuli types, including temperature, pH, Ca2+, CO2 bubbling and biomarker displacement. Supramolecular vesicles were used to load and deliver anti‐ tumor drug doxorubicin to HeLa cells in vitro.

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