Supramolecular structure design of block copolymer by combining 3D confined self-assembly with selective disassembly

Abstract

3D confined self-assembly (3D-CSA) of block copolymer (BCP) is a significant way to generate polymer microparticles with ordered internal suprastructures. Subsequent selective disassembly of the suprastructures can lead to the formation of unique anisotropic micelles or mesoporous microparticles, which can be hardly achieved by solution self-assembly or disassembly of bulk suprastructures. These micelles or mesoporous microparticles and their composites with functional molecules/nanoparticles have great potential in interfacial compatibilization, catalysis, controlled drug delivery and other fields, thus arising increasing attention in recent years. In this review, we first briefly discuss the influence factors, particularly, packing parameter and interfacial selectivity on morphology of BCP assemblies under 3D confinement. Then, we emphasize recent progress in selective disassembly of BCP microparticles into anisotropic micelles or mesoporous microparticles and derived composites. Finally, the outlook and challenges of this direction are highlighted.