Supramolecular Self-Assembly of Atomically Precise Silver Nanoclusters with Chiral Peptide for Temperature Sensing and Detection of Arginine.

Wenjuan Wang,Shulin Li,Di Sun,Zhi Wang,Xia Xin,Quanhua Deng

doi:10.3390/nano12030424

Wenjuan Wang, Shulin Li + Show 4 more

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https://doi.org/10.3390/nano12030424

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Journal: Nanomaterials	Publication Date: Jan 27, 2022
Citations: 25	License type: CC BY 4.0

Affiliation: Shandong University

Abstract

Metal nanoclusters (NCs) as a new type of fluorescent material have attracted great interest due to their good biocompatibilities and outstanding optical properties. However, most of the studies on metal NCs focus on the synthesis, atomic or molecular assembly, whereas metal NCs ability to self-assemble to higher-level hierarchical nanomaterials through supramolecular interactions has rarely been reported. Herein, we investigate atomic precise silver NCs (Ag9-NCs, [Ag9(mba)9], where H2mba = 2-mercaptobenzoic acid) and peptide DD-5 were used to induce self-assembly, which can trigger an aggregation-induced luminescence (AIE) effect of Ag9-NCs through non-covalent forces (H-bond, π–π stacking) and argentophilic interactions [Ag(I)–Ag(I)]. The large Stokes shift (~140 nm) and the microsecond fluorescence lifetime (6.1 μs) indicate that Ag9-NCs/DD-5 hydrogel is phosphor. At the same time, the chirality of the peptide was successfully transferred to the achiral Ag9-NCs because of the supramolecular self-assembly, and the Ag9-NCs/DD-5 hydrogel also has good circularly polarized luminescence (CPL) properties. In addition, Ag9-NCs/DD-5 luminescent hydrogel is selective and sensitive to the detection of small biological molecule arginine. This work shows that DD-5 successfully induces the self-assembly of Ag9-NCs to obtain high luminescent gel, which maybe become a candidate material in the fields of sensors and biological sciences.

Highlights

IntroductionAs a bridge between atom and nanoparticle, metal nanoclusters (metal NCs, mainlyAu, Ag and Cu) which are composed of a few to hundreds of mental atoms and covered with organic ligands on the surface of the metal core, have been receiving extensive attention due to their important roles in the fields of catalysis, sensing, electrochemistry, energy transfer and biomedicine [1,2,3,4,5]
As a bridge between atom and nanoparticle, metal nanoclusters which are composed of a few to hundreds of mental atoms and covered with organic ligands on the surface of the metal core, have been receiving extensive attention due to their important roles in the fields of catalysis, sensing, electrochemistry, energy transfer and biomedicine [1,2,3,4,5]
The current research on Ag NCs is mainly focused on the synthesis and atomic or molecular assembly, while the nanostructures obtained by the means of supramolecular self-assembly are rarely

Summary

Introduction

As a bridge between atom and nanoparticle, metal nanoclusters (metal NCs, mainlyAu, Ag and Cu) which are composed of a few to hundreds of mental atoms and covered with organic ligands on the surface of the metal core, have been receiving extensive attention due to their important roles in the fields of catalysis, sensing, electrochemistry, energy transfer and biomedicine [1,2,3,4,5]. As a bridge between atom and nanoparticle, metal nanoclusters Metal nanoclusters are widely used as sensors because of their sensitive responses to temperature, pH value, metal ions and small biological molecules [6,7,8,9,10]. Can significantly enhance the fluorescence emission of BSA-AuNCs, and constructed an. La3+ ion-BSA-AuNCs fluorescence sensor, realizing the detection of four divalent metal ions (Hg2+ , Cy2+ , Pb2+ and Cd2+ ) [9]. The biocompatibility and fluorescent properties are potentially useful in biological systems of Ag NCs, making them a research hotspot [11]. The current research on Ag NCs is mainly focused on the synthesis and atomic or molecular assembly, while the nanostructures obtained by the means of supramolecular self-assembly are rarely

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