Supramolecular assembly of two copper(II) coordination compounds of topiroxostat with dialkylformamide ligands

Abstract

Abstract A well-known selective xanthine oxidase inhibitor topiroxostat, 4-[3-(4-pyridinyl)-1H-1,2,4-triazol-5-yl]-2-pyridinecarbonitrile (ptpc), was selected to react with Cu(NO3)2 · 3H2O in dialkylformamide solvents, affording two novel supramolecular coordination compounds [Cu(ptpc)2(NO3)(DMF)2] · NO3 (1) and Cu(ptpc)2(NO3)2(DEF)2 (2). Single-crystal X-ray diffraction revealed that compound 1 crystallizes in the monoclinic space group C2/c. The components are assembled to a 3D supramolecular framework through hydrogen-bonding interactions between the large [Cu(ptpc)2(NO3)(DMF)2]+ cationic moieties and the nitrate anions. Compound 2 crystallizes in the triclinic space group P1̅ and shows a 2D hydrogen-bonded network structure. The results clearly indicate that dialkylformamide solvents with different sizes have an important influence on the structures of the complexes. The luminescence properties of 1 and 2 in the solid state and their thermal stabilities were also investigated.