Abstract
Infections by Herpes Simplex Virus (HSV) are widespread and have a large range of clinical manifestations. Recurrent infections usually appear in the same area as the primary infection but not always on the exact same spot. Some people never have any clinical symptoms after the HSV primoinfection whereas others might experience various forms of recurrent HSV infections, i.e. ocular, genital, or muco-cutaneous manifestations. In HSV primoinfections as well as in recurrent infections, the immune status of the patient is very important. Guidelines for the management of HSV primoinfections have been published, taking into account the location, spread and severity of the infection,1 and also in case of immunosuppression and for neonates.
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