Abstract
1. 1. Female European eels, Anguilla anguilla, were given a single intra-arterial injection via a catheter of cortisol hemisuccinate at doses ranging from 3.5 to 35 μg (15 to 150 μg/kg body wt), yielding mean plasma cortisol levels of 87–110 ng/ml 2hr after injection. 2. 2. Cortisol treatment (17.5 and 35 μg) significantly decreased plasma levels of thyroxine (T 4) and triiodothyronine (T 3) within 24 hr relative to those in control fish. 3. 3. Cortisol treatment (35 μg) appeared to increase the clearance rate of 125I-T 3 from plasma and the proportionate uptake of radioactivity in certain tissues after injection of 125I-T 3. 4. 4. Cortisol treatment had no apparent effect on the plasma clearance of 125I-T 4 or tissue distribution of radioactivity after injection of 125T 4.
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