Abstract
Background: Leucine zipper/EF hand-containing transmembrane-1 (LETM1) is a mitochondrial inner membrane protein that encodes for the human homologue of yeast Mdm38p. It is a mitochondria-shaping protein of uncertain function. However, a previous study showed that LETM1 served as an anchor protein for complex formation between mitochondria and ribosome, and regulated mitochondrial biogenesis.
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