Abstract
The electroclinical and neuroimaging features, and response to antiepileptic drugs in 12 children with seizures involving the supplementary sensory motor area (SSMA) are reported from the British Columbia’s Children’s Hospital, Vancouver, BC, Canada.
Highlights
A syndrome of undetermined cause, with onset before age 6 months, nearly continuous multifocal seizures, and progressive psychomotor deterioration is described in 14 children examined in the Universite Rene Descartes, and Hopital Saint Vincent de Paul, Paris, France
This study confirms that clinical features are unreliable markers of seizures in neonates, especially in those receiving antiepileptic drugs
Prolonged video/EEG monitoring is essential for confirmation of seizure control
Summary
NEONATAL SEIZURE CHARACTERISTICS Seizure characteristics in 32 neonates were studied prospectively using prolonged video/EEG recording at the Prince of Wales Children's Hospital, Sydney, Australia. Seizures were generally frequent with limited electrographic spread. Of 1420 seizures recorded, 85% had no clinical manifestations. Clinical observations underestimated electrographic seizures in 54% of neonates. The use of portable EEG machines with only 4 electrodes underestimated seizures in 19 neonates and failed to recognize seizures present in 2. Seizures were generally recorded in both hemispheres, but restricted spread of the seizure discharge necessitated full electrode placements for identification. (Reprints: Dr AME Bye, Department of Paediatric Neurology, Prince of Wales Children's Hospital, High Street, Randwick, 2031, NSW, Australia). This study confirms that clinical features are unreliable markers of seizures in neonates, especially in those receiving antiepileptic drugs. Prolonged video/EEG monitoring is essential for confirmation of seizure control
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
