Supplementary Materials and Methods; Supplementary Tables 1-6; and Supplementary Figure Legends from Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity

Abstract

<p>Additional data showing pharmacological characterization of Mps1 Inhibitors BAY 1161909 and BAY 1217389; Suppl. Table 1: Kinase selectivity profile of BAY 1161909; Suppl. Table 2: Kinase selectivity profile of BAY 1217389; Suppl. Table 3: Kinase selectivity profiles of BAY 1161909 compared to SP600125 and Reversine; Suppl. Table 4: Inhibition of tumor cell proliferation by BAY 1161909 or BAY 1217389; Suppl. Table 5: Summary of in vivo activity of BAY 1161909 in human xenograft tumor models in mice; Suppl. Table 6: Summary of in vivo activity of BAY 1217389 in human xenograft tumor models in mice.</p>