Supplementary Figures 1 through 5 from Synergistic Activities of MET/RON Inhibitor BMS-777607 and mTOR Inhibitor AZD8055 to Polyploid Cells Derived from Pancreatic Cancer and Cancer Stem Cells

Abstract

<p>PDF - 424K, Supplementary Figure 1. Effect of BMS-777607 alone or in combination with AZD8055 on polyploidy and viability of Panc1 and BxPC3 cells; Supplementary Figure 2. Effect of siRNA-mediated knockdown of RON expression on BMS-777607-induced polyploidy; Supplementary Figure 3. Effect of BMS-777607 on DNA/chromosome content in L3.6pl cells and CSCs+24/44/ESA; Supplementary Figure 4. Effect of BMS-777607 alone or in combination with AZD8055 on apoptosis of L3.6pl cells; Supplementary Figure 5. Effect of BMS-777607 alone or plus AZD8055 on MCL1 and cyclin B expression in L3.6pl cells.</p>