Abstract

<p>(a) Quantitative analysis of PD-L1 mRNA and protein expression compared TP53 mutation with TP53 wild type tumor. (b) Quantitative analysis of PD-L1 mRNA and protein expression compared KRAS mutation with KRAS wild type tumor. (c) Immunohistochemistry (IHC) analysis of PD-L1 expression (strong: {greater than or equal to}50% vs. weak: 1-49% vs. negative: <1%) based on TP53 mutation status in a cohort of 93 lung adenocarcinoma. NS, no significant; mut, mutation; wt, wild type; *** P < 0.001, * P < 0.05</p>

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