Supplemental figures from Dietary Emulsifier–Induced Low-Grade Inflammation Promotes Colon Carcinogenesis

Abstract

<p>Figure S1: Schematic representation of the AOM-DSS experimental design. Figure S2: Dietary emulsifiers promote metabolic syndrome and low-grade intestinal inflammation in WT mice. Figure S3: Colonic histology analysis of emulsifiers promotion of colitis-associated cancer. Figure S4: Dietary emulsifiers induce alterations of the microbiota. Figure S5: Alpha diversity and summarized taxa of the fecal bacterial community following emulsifier treatment. Figure S6: Identification of bacterial members differentially expressed between experimental groups. Figure S7: Dietary emulsifiers favor a pro-inflammatory microbiota. Figure S8: Metagenome prediction analysis following CMC consumption. Figure S9: Metagenome prediction analysis following P80 consumption. Figure S10: Dietary emulsifiers alter epithelial cell proliferation and apoptosis during colitis-associated cancer development. Figure S11: Dietary emulsifier and AOM injection experiment.</p>