Abstract

Since publication of the 2004 update to the American Association of Physicists in Medicine (AAPM) Task Group No. 43 Report (TG-43U1), several new low-energy photon-emitting brachytherapy sources have become available. Many of these sources have satisfied the AAPM prerequisites for routine clinical use as of January 10, 2005, and are posted on the Joint AAPM/RPC Brachytherapy Seed Registry. Consequently, the AAPM has prepared this supplement to the 2004 AAPM TG-43 update. This paper presents the AAPM-approved consensus datasets for these sources, and includes the following 125I sources: Amersham model 6733, Draximage model LS-1, Implant Sciences model 3500, IBt model 1251L, IsoAid model IAI-125A, Mentor model SL-125/ SH-125, and SourceTech Medical model STM1251. The Best Medical model 2335 103Pd source is also included. While the methodology used to determine these data sets is identical to that published in the AAPM TG-43U1 report, additional information and discussion are presented here on some questions that arose since the publication of the TG-43U1 report. Specifically, details of interpolation and extrapolation methods are described further, new methodologies are recommended, and example calculations are provided. Despite these changes, additions, and clarifications, the overall methodology, the procedures for developing consensus data sets, and the dose calculation formalism largely remain the same as in the TG-43U1 report. Thus, the AAPM recommends that the consensus data sets and resultant source-specific dose-rate distributions included in this supplement be adopted by all end users for clinical treatment planning of low-energy photon-emitting brachytherapy sources. Adoption of these recommendations may result in changes to patient dose calculations, and these changes should be carefully evaluated and reviewed with the radiation oncologist prior to implementation of the current protocol.

Highlights

  • The 1995 report from the American Association of Physicists in MedicineAAPM Task Group No 43 ͑TG-43͒1 on the dosimetry of interstitial brachytherapy sources was updated in 2004, and was termed the AAPM TG-43U1 report.2–6 The1995 report contained recommended datasets for four interstitial brachytherapy sources: Amersham-Health models 6702 and 6711 sources of 125I, the Theragenics Corporation2187 Med

  • In the 2004 update, the AAPM updated the data on the 125I and 103Pd sources included in the original report and included data on six other interstitial brachytherapy sources

  • Imagyn isostar model IS-12501 125I sourcenote that the Imagyn isostar model IS-12501 125I source which was included in the 2004 AAPM TG-43U1 report has been removed from the online Joint AAPM/RPC Source Registry due to discontinuation by the manufacturer, 7

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Summary

INTRODUCTION

The 1995 report from the American Association of Physicists in MedicineAAPM Task Group No 43 ͑TG-43͒1 on the dosimetry of interstitial brachytherapy sources was updated in 2004, and was termed the AAPM TG-43U1 report. The. The. 1995 report contained recommended datasets for four interstitial brachytherapy sources: Amersham-Health models 6702 and 6711 sources of 125I, the Theragenics Corporation. Rivard et al.: Supplement to AAPM TG-43 update model 200 source of 103Pd and the Best Medical 192Ir sourcecertain commercial equipment, instruments, and materials are identified in this work in order to specify adequately the experimental procedure. As planned during the writing of TG-43U1, a supplement was needed to present consensus datasets for these newer sources This supplement is termed TG-43U1S1, and includes the following sources which met the criteria mentioned above as of January 10, 2005: 1.

CONSENSUS DATASETS FOR CLINICAL IMPLEMENTATION
CLARIFICATIONS ON RECOMMENDED INTERPOLATION AND EXTRAPOLATION METHODS
Radial dose function
SUMMARY
Amersham model 6733 125I source
Draximage model LS-1 125I source
LS-1 Λ
Implant Sciences model 3500 125I source
IBt model 1251L 125I source
IsoAid model IAI-125A 125I source
IsoAid IAI-125A Λ
Source Tech Medical model STM1251 125I source
STM1251 Λ
Findings
Best Medical model 2335 103Pd source
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