Abstract
Supervised Treatment Interruptions Fail to Control HIV-1 Viremia
Highlights
Hill and his co-workers used a heterologous prime–boost vaccination technique
A malaria vaccine called ME-thrombospondin-related adhesion protein (TRAP), which targets the preerythrocytic stage of the disease, was not effective at reducing natural infection rates in semi-immune African adults, according to the report of a randomized controlled trial published this month in PLoS Medicine
They gave the volunteers two vaccines—a DNA priming vaccine followed by a modified vaccinia virus Ankara (MVA) that acted as a booster
Summary
Hill and his co-workers used a heterologous prime–boost vaccination technique. They gave the volunteers two vaccines—a DNA priming vaccine followed by a modified vaccinia virus Ankara (MVA) that acted as a booster. A malaria vaccine called ME-TRAP, which targets the preerythrocytic stage of the disease, was not effective at reducing natural infection rates in semi-immune African adults, according to the report of a randomized controlled trial published this month in PLoS Medicine.
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