SUPEROXIDE DISMUTASE AND MALONDIALDEHYDE LEVELS IN ADOLESCENTS WITH PRIMARY DYSMENORRHEA

Abstract

Primary dysmenorrhea is painful menstruation without pelvic abnormalities and it usually occurs among adolescents and female adults. Primary dysmenorrhea processing the increasing of lipid peroxide (oxidative stress) and decreasing of antioxidant level. The aim of this study to identified the differences of Superoxide Dismutase and Malondialdehyde levels among adolescents with primary dysmenorrhea. The research design used Case Control. The population of this study were all female students at Health Science Faculty of Unipdu Jombang who got menstruation, the sample of this study were 24 respondents who met the inclusion and exclusion criteria. Sampling method in this study used Purposive Sampling technique. NBT method was to measured SOD levels, Thiobarbituric Acid (TBA) test used to measured MDA levels, and the measurement in this study used Spectrophotometer. The data analysed by using Independent Sample T-Test with α ≤ 0.05. Independent Sample T-Test results showed that there were significant differences between SOD and MDA levels in both of case group and control group (p