Abstract
As retinal amyloid deposition correlate with and even precede brain amyloidosis, retinal imaging may become a non-invasive and non-ionizing biomarker for Alzheimer's disease. Retinal autofluorescencence using a specific amyloid-binding fluorophore curcumin and laser ophthalmoscopy is an emerging methodology for retinal amyloid quantification. In this study, we aimed to evaluate the relationship between the retinal amyloid counts (RAC) in the supero-temporal quadrant and brain volumes, and cognitive performance.
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