Abstract
BackgroundThe aim of this study is to investigate the physicochemical and structural properties of Medifoam®Silver and to compare with other commercially available silver-containing polyurethane (PU) foam dressing in vitro.MethodsSurface and cross-section of four polyurethane foam dressings were assessed with field-emission scanning electron microscope. Thickness, density, tensile strength, elongation, absorption rate, absorption/retention capacity and water-vapor transmission (WVT) were measured to compare physical properties of various dressing materials.ResultsAmong four tested dressings, Medifoam®Silver has relatively uniform and smallest pore size in both surface and cross-section. In comparison of absorption properties with other dressing materials, Medifoam®Silver has rapid absorption rate, good absorption/retention capacity and good WVT value.ConclusionsThe data further suggests that Medifoam®Silver is a promising candidate for wound healing management.
Highlights
The aim of this study is to investigate the physicochemical and structural properties of Medifoam®Silver and to compare with other commercially available silver-containing polyurethane (PU) foam dressing in vitro
We showed that our wound dressing, Medifoam® N, has excellent physicochemical properties when compared with other dressing materials [13]
We showed that appropriate physicochemical properties of wound dressing material such as porous structure, thickness/ density, tensile strength and moisture-vapor transmission rate contributed to improve performance of wound dressing material
Summary
The aim of this study is to investigate the physicochemical and structural properties of Medifoam®Silver and to compare with other commercially available silver-containing polyurethane (PU) foam dressing in vitro. Topical silver creams and solutions have been extensively used for wound healing since they offer a broad spectrum of antimicrobial activity, less development of resistance, fewer adverse reactions, and a low risk of systemic toxicity [7, 8]. These agents normally require frequent application, care-intensive application/removal, and cause painful reaction in patients [8–10]. Many reports describe that silver-based dressings are helpful to overcome bacterial infections, to promote environment for granulation/re-epithelialization
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