Superinfection exclusion und DNA-Injektion bei Siphoviridae-Phagen

Abstract

Superinfection exclusion (SIE) is a mechanism by which a prophage residing in the genome of its host bacterium prevents infection of its host by other phages. During recent years, we have studied superinfection exclusion by prophage TP-J34. Its host is Streptococcus thermophilus J34, a bacterium applied as yoghurt starter. Here we present our data on identifying the SIE protein of TP-J34, its mode of action, X-ray structure, and target protein in the superinfecting phage.