Superbugs: An invicible threat in post antibiotic era

Abstract

BackgroundSuperbug resistance is a very rare, invincible global problem arising as a threat in hospitals as well as in the community. Methicillin-Resistant Staphylococcus aureus(MRSA), Vancomycin-Resistant Enterococci (VRE) and Multidrug-resistant Gram-negative bacilli (MDR-GNB) etc are the most deadly contagious strains. This study discloses the prevalence and risk factors associated with superbugs there by aiding the adoption of preventive measures to reduce resistance patterns in hospital settings. AimIdentification of the superbug that predominantly shows antibiotic resistance in hospitals and analyzing the risk factors for the occurrence of antibiotic resistance. Materials and methodsA prospective observational study was conducted for one year, from 1st September 2019 to 31st July 2020 to evaluate the prevalence and risk factors of antibiotic-resistant superbugs among the 80 patients selected from the various departments (General Medicine, General Surgery, Nephrology, Pulmonology,Orthopedics, orthopaedicsurgery,Neurology, Urology,and Neurosurgery) of a tertiary care referral hospital. ResultsMethicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa were antibiotic-resistant superbugs that predominantly showed resistance in hospital settings. ConclusionPseudomonas aeruginosa and Methicillin-resistant superbugs were the predominantly found superbugs in hospital settings. Major risk factors for antibiotic-resistant superbugs were found to be Prolonged hospitalization, previous antibiotic therapy, failure to take the antibiotic as prescribed by physicians, patient co-morbid conditions, prophylactic use of antibiotics, patient diet etc.