SUN-207 MAGNESIUM LEVELS IN DIABETIC PATIENTS WITH END STAGE RENAL DISEASE (ESRD) IN ONE CENTER IN THE UNITED ARAB EMIRATES (UAE)

I Alshamsi,M Hassan,A Saleh,K Al Mutawa,E Khater,N Luqman,N Richards

doi:10.1016/j.ekir.2020.02.741

I Alshamsi, M Hassan + Show 5 more

Open Access

https://doi.org/10.1016/j.ekir.2020.02.741

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Abstract

Diabetic kidney disease is the primary aetiology of ESRD in the UAE1. Low magnesium has been associated with poor glycaemic control and complications including diabetic kidney disease2. Large cohort studies from Japan and the United States reported low mean serum magnesium among 1.6-20% of their dialysis population3,4. Lower magnesium level was found to be more prevalent in diabetic patient in the Japanese cohort. ESRD patients with low magnesium and low normal magnesium had higher cardiovascular and non-cardiovascular mortality3,4. Aim: To compare the prevalence of magnesium disorders among diabetic patients with ESRD and non-diabetic patients with ESRD. The study is a single centre cross sectional study that was conducted at Sheikh Khalifa Medical City (SKMC) dialysis centre in Abu Dhabi, UAE. Exclusion criteria included patients who do not regularly dialyse at our centre and those who had less than four readings of magnesium level during the study period. The study period was from January 2017 to December 2017. A total of 260 patients were included in the study. The majority (70%) of the patients were non Emirati nationals. 41% were females, and the mean age was 55 years. The mean magnesium among our patients was 0.98 mmol/L with a SD +/- 0.15. The normal reference range is 0.66-1.07 mmol/L (1.6-2.6 mg/dL). The 12 months mean magnesium readings were calculated for all the patients. None of our patients had a low average magnesium. 21.6% of our patients had high average magnesium levels, while 78.4% had normal average magnesium levels. 59% of Emirati patients compare to 40% of non-Emirati patients were diabetic. There was no statistically significant relationship between Magnesium level and DM status (0.14 respectively). None of our patients had an average low magnesium. There was no statistically significant difference between normal magnesium levels and being diabetic among dialysis patients in our centre.

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