SUN-PP095: Systemic Muscle Dysfunction in Chronic Heart Failure Is Associated with Enhanced Myofibrillar Protein Breakdown but Preserved Muscle Mass

Abstract

to analyze body mass index (BMI) with nutritional and body composition parameters in institutionalized older people. Methods: Cross-sectional study in 104 normal-weight older people (73% female, mean of: age 86.4±6.2 years, time on institutionalization 25.7±21.7 months). Nutritional assessment by Mini-Nutritional Assessment, anthropometric measures and biochemical parameters. Body composition analysis measured bioelectrical impendance (BIVA-RJL System). Sample was classified into BMI tertiles (Tn): T1:26.2; T2: 26.3 29.7, y T3: 29.8 kg/m2. Statistical analysis by SPSS v. 19. Results: Mean of BMI 28.4±4.6 and obesity 31.7%. Prevalence of nutritional risk or malnutrition was 60.6 and 11.5%, respectively. BMI showed significant differences into tertiles with: mid-arm muscle circumference, triceps-skinfold thickness, total body water (all, P< 0.001). Comparison between BMI tertiles (T1 vs. T2 and T3) and nutritional status showed that subjects into T1 had significantly higher nutritional risk or malnutrition (Mean BMI T1 vs. T2 and T3: 23.7 vs. 27.7 and 33.7). Linear regression analysis showed significant relation between BMI and waist circumference, calf-circumference (both, p < 0.01) and inverse with total body water (p < 0.001) (R = 0.71). Conclusion: The current classification of BMI should be evaluated in older people. Overweight and obesity measured by BMI is not an exclusion criteria of nutritional risk or malnutrition in elders. Further longitudinal analyses are required to define cut-off points of BMI in elderly population.