SUN-166 FACTORS THAT CONFOUND THE PREDICTION OF RENAL MEDULLARY OXYGENATION AND RISK OF ACUTE KIDNEY INJURY FROM MEASUREMENT OF BLADDER URINE OXYGEN TENSION

Y.R Lankadeva,J.A Smith,M.Z.L Zhu,C.N May,J.P Ngo,R.G Evans,M Kanki,A.D Cochrane,A Martin,A.G Thrift

doi:10.1016/j.ekir.2019.05.568

SUN-166 FACTORS THAT CONFOUND THE PREDICTION OF RENAL MEDULLARY OXYGENATION AND RISK OF ACUTE KIDNEY INJURY FROM MEASUREMENT OF BLADDER URINE OXYGEN TENSION

Y.R Lankadeva, J.A Smith + Show 8 more

Open Access

https://doi.org/10.1016/j.ekir.2019.05.568

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Journal: Kidney International Reports	Publication Date: Jul 1, 2019
License type: cc-by-nc-nd

Affiliation: Florey Institute of Neuroscience and Mental Health, Monash Health, Australian Regenerative Medicine Institute, Monash University

#Urinary PO2 #Urinary Oxygen Tension + Show 8 more

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Abstract

Urinary oxygen tension (PO2) may provide a useful estimate of renal medullary PO2 and thus risk of acute kidney injury (AKI). However, the relationship between urinary PO2 and medullary PO2 could be confounded by variations in urine flow and arterial PO2. In the current study we exploited data we had previously generated, from experimental studies in ovine septic AKI and in patients undergoing cardiac surgery requiring cardiopulmonary bypass (CPB), to perform a detailed analysis of the influences of urine flow and arterial PO2 on urinary PO2.

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