SUN-063 Evaluation of serum selenium level and its related factors in hemodialysis patients

Abstract

Selenium (se) is an essential dietary trace element that influences immune system, reproductive system, DNA synthesis, antioxidant defence and has a key role in a wide variety of metabolic pathways and biological processes. Many studies have shown that serum selenium level is reduced in hemodialysis patients. This paper tries to measure and examine the influence of age, duration of dialysis and KT/V on the selenium level in hemodialysis patients. A descriptive cross-sectional study was designed. Data was collected by using patient’s file and sending blood sample to the lab. Through using the sample measurement method, the sample size has come to 215. But due to limitations we could only collect 189 patient’s data. Data were analyzed by Pearson correlation coefficient using SPSS (Ver. 22) software. The mean level of selenium in hemodialysis patients (15-79 years old) was 44.4±9.7 μg/dl. There was a significant relationship between serum selenium level and KT/V (p=0.04) but there was no significant relationship between serum selenium and age (p=0.79), dialysis duration (p=0.77), dialysis weekly (p=0.99), duration of dialysis year (p=0.11) (p>0.05). According to the key role of selenium in cardiovascular disease, anemia, cancer, immune system and its importance to hemodialysis patients we can prevent these by controlling selenium level properly. This study would have benefited from a bigger sample size and measurement of selenium level in normal people.