Abstract
The second ISCB-Asia conference of the International Society for Computational Biology took place December 17-19, 2012, in Shenzhen, China. The conference was co-hosted by BGI as the first Shenzhen Conference on Computational Genomics (SCCG).45 talks were presented at ISCB-Asia/SCCG 2012. The topics covered included software tools, reproducible computing, next-generation sequencing data analysis, transcription and mRNA regulation, protein structure and function, cancer genomics and personalized medicine. Nine of the proceedings track talks are included as full papers in this supplement.In this report we first give a short overview of the conference by listing some statistics and visualizing the talk abstracts as word clouds. Then we group the talks by topic and briefly summarize each one, providing references to related publications whenever possible. Finally, we close with a few comments on the success of this conference.
Highlights
ISCB-Asia/Shenzhen Conference on Computational Genomics (SCCG) 2012 was immediately followed by the Asian Young Researchers Conference on Computational and Omics Biology (AYRCOB), cohosted by BGI
The talks were given by researchers from 16 countries, representing many of the leading centers of bioinformatics research worldwide, and the selection of topics was, in the opinion of the authors of this report, quite representative of modern-day trends in computational biology (Figures 1, 2)
We subjectively conclude that ISCB-Asia/SCCG 2012 was without doubt a successful event
Summary
Following the success of the first ISCB-Asia, held jointly with APBioNET as InCoB/ISCB-Asia 2011 [1,2], ISCBAsia/SCCG 2012 took place on December 17-19, 2012, in Shenzhen, China. An interesting method for performing phylogenetic analysis on NGS data without the need to assemble reads was presented in a highlights talk by Urmila KulkarniKale [19] of the University of Pune. A keynote by Zhiping Weng (University of Massachusetts Medical School) introduced Factorbook [30], a de novo motif discovery analysis performed on ENCODE data; and Stephen Kwok-Wing Tsui (The Chinese University of Hong Kong) presented a method of discovering Protein-DNA binding sites using association rule mining [31]. A tool for non-invasive prenatal diagnosis, FetalQuant [48], was presented in a highlights talk by Hao Sun (The Chinese University of Hong Kong) This tool estimates fractional fetal DNA concentration directly from massively parallel sequencing on DNA in maternal plasma, eliminating the need for prior genotype information. Yuanhui Xiao (Georgia State University) presented analysis of retinal pigment epithelium flatmount images
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