Abstract
Major changes and updates of Clinical and Laboratory Standards Institute (CLSI) document M100-S22 for performance standards for antimicrobial susceptibility testing were introduced in the article, which includes (1) general changes; (2) changes of drugs recommended for testing and reporting; (3) changes of interpretive criteria (breakpoints) and comments; (4) changes of quality control and others; and (5) changes of appendixes and glossaries.（Chin J Lab Med,2012,35:676-678） Key words: Antimicrobial agents; Microbial sensitivity tests; Publications
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