Abstract

Summaries for Patients1 October 2002The Genetics of Colorectal CancerSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-7-200210010-00005 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Colorectal cancer, which affects the colon [large intestine] or rectum, is a common type of cancer. Most cases occur in people with no special genetic susceptibility to colorectal cancer. However, some cases of colorectal cancer occur in people whose genes put them at high risk. Their colorectal cancer can be either inherited or familial. Colorectal cancer is inherited in fewer than 10 out of every 100 cases. People with inherited colorectal cancer have polyposis or nonpolyposis syndromes. In polyposis syndromes, patients develop many polyps in their colons. Some ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “The Genetics of Colorectal Cancer.” It is in the 1 October 2002 issue of Annals of Internal Medicine (volume 137, pages 603-612). The authors are PM Calvert and H Frucht.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Genetics of Colorectal Cancer Paula M. Calvert and Harold Frucht Metrics 1 October 2002Volume 137, Issue 7Page: I-48KeywordsCancer geneticsCancer preventionCancer screeningColonColorectal cancerGenetic counselingMismatch repairMutationRectumTumor suppressor genes ePublished: 1 October 2002 Issue Published: 1 October 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

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