Abstract
A novel sulfur- and peroxy-bridged twelve-membered macrolide, cladosporioidin A (1), and a new iodinated dimeric naphtho-γ-pyrone, (aS)-6-iodofonsecinone A (2), were obtained from a marine cold-seep isolate (8-1) of Cladosporium cladosporioides. Their structures and relative/absolute configurations were unequivocally established by combination of various spectroscopic techniques, mainly including NMR, MS, and ECD. Compounds 1 and 2 were assayed to feature antimicroalgal and antibacterial activities.
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