Abstract
An efficient domino approach for the synthesis of new pyrano[4,3-b]pyrazolo[4,3-e]pyridin-5(1H)-one derivatives has been developed using reusable sulfonic organic resin as catalyst in water. The unique feature of sulfonic organic resin makes the formation of pyrano[4,3-b]pyrazolo[4,3-e] pyridin-5(1H)-ones be possible, and avoids generating ring opening products. The plausible mechanism for this domino reaction is proposed.
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