Abstract

A simple and energy-efficient green protocol for the synthesis of a series of biologically interesting functionalized bis-lawsone [i.e., 3,3′-(aryl/alkyl-methylene)bis(2-hydroxynaphthalene-1,4-dione)] scaffolds has been developed in the presence of sulfamic acid as an eco-friendly organocatalyst via one-pot pseudomulticomponent reaction at room temperature. The salient features of the present protocol are mild reaction conditions, good to excellent yields, operational simplicity, energy-efficiency, high atom-economy, eco-friendliness, easy isolation of products and no column chromatographic separation.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call