Abstract
<h3>Objective.</h3> —To assess the potential availability and utility of fetal tissues obtained from spontaneous abortions and from ectopic pregnancies for human transplantation therapy. <h3>Design.</h3> —Tissue collection and analysis by personnel skilled in tissue banking. <h3>Setting.</h3> —Procurement programs in five tissue banks located in diverse geographical areas that are funded by the National Institutes of Health. <h3>Patients.</h3> —All women entering obstetric clinics during 1993 who consented to participate in the study. <h3>Interventions.</h3> —None. <h3>Main Outcome Measures.</h3> —Evaluation of the products of conception by standard developmental, histological, microbiological, and cytogenetic criteria. <h3>Results.</h3> —From 22235 obstetric admissions, 1250 spontaneously aborted embryos and 247 products of ectopic pregnancies were obtained. Of these, seven embryos (0.5%) were potentially useful for human transplantation therapy. <h3>Conclusion.</h3> —Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy. (<i>JAMA</i>. 1995;273:66-68)
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