Abstract

BackgroundSuicide is the second leading cause of death for college-aged individuals worldwide and in the United States. Recent studies have identified preliminary evidence of widening disparities in suicidal behaviors across sex, sexual orientation, race/ethnicity, age, and socioeconomic status among college students. Few systematic reviews and meta-analyses offer a comprehensive understanding of on-campus and off-campus suicide interventions, nor is collated information available for different types of screening, assessment, treatment, and postvention plans. Further challenges have been identified since the COVID-19 pandemic, calling for cost-effective and innovative interventions to address increased rates of suicidal behaviors among college students facing unprecedented stressors.ObjectiveThis research protocol describes the first systematic review and meta-analysis to identify the most effective and cost-effective intervention components for universal and targeted (indicated and selected) suicide prevention among college students in a global context. Special attention will be placed on disparities in suicide prevention across sociodemographic subgroups, inclusive interventions beyond campus, global context, and intervention responses to the COVID-19 pandemic.MethodsA sensitive search strategy will be executed across MEDLINE (Ovid), EMBASE, PsycINFO (EBSCO), ERIC (EBSCO), Cochrane Library, Dissertations and Theses Global (ProQuest), Scopus, Global Index Medicus, SciELO, African Journals Online, Global Health (CABI), and Google Scholar. Data extraction and evaluation will be conducted by three independent researchers. Risk of bias will be assessed. A multilevel meta-regression model and subgroup analysis will be used to analyze the data and estimate effect sizes.ResultsThe initial search was completed in December 2020 and updated with additional other-language studies in March 2020. We expect the results to be submitted for publication in mid-2021.ConclusionsDespite increasing rates of suicidal behaviors among college students, few preventative efforts have targeted this population, and fewer focus on factors that might place specific demographic groups at heightened risk. The impact of COVID-19 on suicidal behaviors among college students highlights and exacerbates the urgent need for rapid and effective interventions that might differ from traditional approaches. This equity-focused study will address these gaps and provide a valuable analysis of the effectiveness of suicide prevention programs and interventions. Findings will inform clinicians, researchers, policy makers, families, and organizations about evidence-based interventions for reducing the gaps in the suicide crisis among college students from different sociodemographic groups.Trial RegistrationPROSPERO CRD42020225429; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=225429International Registered Report Identifier (IRRID)DERR1-10.2196/26948

Highlights

  • BackgroundSuicide is the second leading cause of death for college-aged individuals worldwide and in the United States [1,2,3,4,5,6,7]

  • The impact of COVID-19 on suicidal behaviors among college students highlights and exacerbates the urgent need for rapid and effective interventions that might differ from traditional approaches

  • Given our specific focus on at-risk subpopulations and interventions aimed at reducing barriers to seeking help among college students across sex, race/ethnicity, sexual orientation, and socioeconomic status, we further adapted the PRISMA statement on equity-focused systematic reviews (PRISMA-E 2012) [46,64,65,66,67] to improve transparency and completeness in reporting health equity–focused systematic reviews, in addition to the previous PRISMA-E checklist developed by Moher and colleagues [68,69]

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Summary

Introduction

BackgroundSuicide is the second leading cause of death for college-aged individuals worldwide and in the United States [1,2,3,4,5,6,7]. In the United States, one-fifth of college student participants in a recent national survey reported suicidal ideation, with 9% reporting suicide attempts [4]. There is an urgent need for research to develop effective, innovative, and accessible suicide prevention programs and interventions for college students. Suicide is the second leading cause of death for college-aged individuals worldwide and in the United States. Recent studies have identified preliminary evidence of widening disparities in suicidal behaviors across sex, sexual orientation, race/ethnicity, age, and socioeconomic status among college students. Further challenges have been identified since the COVID-19 pandemic, calling for cost-effective and innovative interventions to address increased rates of suicidal behaviors among college students facing unprecedented stressors

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