Abstract
In a review of 495 infants under 1 mo of age with a variety of surgical conditions, none involving extensive gut resection, 22 were found to have sugar intolerance, an incidence of 4.4%. The incidence of intolerance was highest in babies with small-bowel obstruction (30%), but a number of infants with esophageal atresia, imperforate anus, Hirschsprung's disease, and abdominal wall defects were also affected. The diagnosis was made clinically by detection of sugar in the stool with Clinitest and a prompt response to withdrawal of the offending sugar (s) from the diet and confirmed by stool and urine chromatography. The intolerance in all cases was to disacchardies and in 86% there was a prompt cessation of diarrhea when these sugars were withdrawn from the diet.
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