Abstract

Before the discovery of insulin, diabetes was a life-threatening and untreatable illness. It was caused by very high blood sugar levels and many children died from it. In 1922, two scientists, Frederick Banting and Charles Best, treated a boy suffering from diabetes with special extracts from a cow’s pancreas. The pancreas is an organ found near the stomach. The treatment lowered the boy’s blood sugar to normal levels due to a chemical substance from the pancreas. This substance was later named insulin. In this article you will read about diabetes and insulin. You will see that the final discovery of insulin built on the work of many scientists before Banting and Best. It is a great story showing how the skills and determination of different people together led to a ground-breaking discovery. In 1978, human insulin was made artificially from bacteria and today it continues to save millions of lives.

Highlights

  • Before the discovery of insulin, diabetes was a life-threatening and untreatable illness

  • Insulin is not produced by the pancreas

  • The body does not respond to insulin and the pancreas does not make enough insulin

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Summary

The Discovery of Insulin

A condition in which glucose levels in the blood become dangerously high. Insulin is not produced by the pancreas. The body does not respond to insulin and the pancreas does not make enough insulin. A chemical substance made by cells in the islets of Langerhans. The main role of insulin is to help the body to use glucose as a source of energy. Carbohydrate from the diet is made up of smaller units. Glucose is the most common and important of these units as it is the main source of energy fuel for the body. A condition in which the blood becomes acidic due to the production of high levels of ketone bodies. When glucose is not available, the liver makes ketone bodies from fat molecules to provide energy for the brain

WHAT IS DIABETES?
DIFFERENT TYPES OF DIABETES
INSULIN RESISTANCE
WHAT CAUSES HIGH LEVELS OF GLUCOSE IN THE BLOOD?
WHAT IS SPECIAL ABOUT THE PANCREAS?
CONTROLS GLUCOSE LEVELS
Banting and MacLeod received the Nobel Prize in
YOUNG REVIEWERS
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